Quantum LogP module (part of q-Mol package) has been benchmarked by vcclab.org

Quantum LogP module (part of q-Mol package) has been reviewed by R. Mannhold et al. (vcclab.org) in "Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of Log P Methods on More Than 96,000 Compounds". From the manuscript:

"Quantum LogP, developed by Quantum Pharmaceuticals, uses another quantum-chemical model to calculate the solvation energy. Like in COSMO-RS, the authors do not explicitly consider water molecules but use a continuum solvation model. However, while the COSMO-RS model simplifies solvation to interaction of molecular surfaces, the new vector-field model of polar liquids accounts for short-range (H-bond formation) and long-range dipole–dipole interactions of target and solute molecules Quantum LogP calculated log P for over 900 molecules with an RMSE of 0.7 and R2 of 0.94".